ABSTRACT
Objective:To analyze the relationship between red cell distribution width (RDW) and disease severity in patients with non-ST-elevation myocardial infarction.Methods:Seventy patients with non-ST-elevation myocardial infarction who received treatment in Chaozhou People's Hospital from June 2019 to June 2020 were included in the observation group. An additional 70 patients with ST-elevation myocardial infarction who concurrently received treatment in the same hospital were included in the control group. All patients underwent electrocardiography and blood biochemical index examination. RDW was compared between the observation and control groups. The relationship between RDW and the severity of non-ST-elevation myocardial infarction was analyzed.Results:RDW in the observation group was significantly higher than that in the control group [(14.60 ± 1.00) % vs. (13.06 ± 1.70) %, t = 5.884, P = 0.012). The detection rate of coronary artery thrombosis in the observation group was significantly higher than that in the control group [70.00% (49/70) vs. 50.00% (35/70), χ2 = 7.563, P = 0.002]. In the observation group, the area under the receiver operating characteristic (ROC) curve plotted taking RDW as the variable was 0.649 (95% CI 0.546-0.753, P = 0.006). When the critical value of RDW was 14%, the sensitivity and specificity of RDW in the prediction of non-ST-elevation myocardial infarction were 73% and 59% respectively. RDW was positively correlated with cardiac troponin I level ( r = 0.19, P = 0.006). Conclusion:In patients with non-ST-elevation myocardial infarction, the increase in RDW is related to myocardial injury and the increase in cardiac troponin I level. RDW can be used as an effective index to predict the severity of non-ST-elevation myocardial infarction.
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Objective To study the effect of intensive atorvastatin therapy on blood glucose in ACS patients.Methods Two hundred ACS patients were divided into control group (n=100) and intensive atorvastatin therapy group (n=100).The patients in both groups underwent secondary preventive treatment of CHD.The patients in control group were treated with 20 mg oral atorvastatin before going to bed and those in intensive atorvastatin therapy group were treated with 40mg oral atorvastatin.The patients were followed up for 6 months,during which their serum levels of FPG,HbA1c,TC,TG,LDL-C and HDL-C were measured before and after treatment.Results The serum levels of HDL-C were significantly higher while those of TC,TG and LDL-C were significantly lower in control group after treatment than before treatment (P＜0.01).The serum levels of HDL-C,FPG and HbA1c were significantly higher while those of TC,TG and LDL-C were significantly lower in intensive atorvastatin therapy group after treatment than before treatment(P＜0.05,P＜0.01).The serum levels of HDL-C,FPG and HbA1c were significantly higher while those of TC and LDL-C were significantly lower in intensive atorvastatin therapy group after treatment than before treatment (1.48±0.39 mmol/L vs 1.36±0.20 mmol/L,P＜0.05;5.71±0.67 mmol/L vs 5.21±0.53 mmol/L,P＜0.01;5.44％±0.75％ vs 5.19％±0.31％,P＜0.01).Conclusion Intensive statin therapy can effectively reduce the serum lipid level,elevate the serum FPG level,and increase the risk of diabetes in ACS patients.
ABSTRACT
BACKGROUND:As a novel noninvasive method, high frequency ultrasound has been used for the detection of skeletal muscle widely. OBJECTIVE:To detect the thickness of the dorsalLisfrancligament between the first (medial) cuneiform (C1) and second metatarsal (M2) using high frequency ultrasound to evaluate the feasibility and clinical application value of high frequency ultrasound for the detection of theLisfrancjoint. METHODS:Both feet of 100 healthy volunteers were included and the thickness of dorsalLisfranc ligament and the distance between C1 and M2wereexamined using high frequency ultrasound. RESULTS AND CONCLUSION:The display rate of high frequency ultrasound for the dorsalLisfranc ligament in the 100 healthy volunteers was 100%. There was no significant difference in the thickness of the dorsalLisfrancligament between both feet or sexes in adults(P> 0.05); as did the distance between C1 and M2 (P> 0.05). These findings suggest that visual dorsalLisfrancligament is detected by high frequency ultrasound. The measurement of the distance between C1 and M2by high frequency ultrasound may be a feasible, noninvasive, low-cost, and early diagnostic method forLisfrancinjuries.